摘要
目的 研究骨髓纤维化合并门脉高压的特点。方法 对已确诊的 6例骨髓纤维化合并门脉高压患者进行胃镜、B超、CT、肝功能、核素心 /肝血流比、骨髓穿刺及活检等检查 ,并有 10例肝硬化患者作对照。结果 6例患者各项肝功能指标基本正常 ,白细胞与血小板数升高 ,骨髓象见纤维组织大量增生。胃镜 6例患者均有食管胃底静脉曲张 ,B超及 CT示肝弥漫性损害 ,均有门静脉增宽及脾大 ,核素心 /肝血流比测门脉压为 32± 2 cm H2 O。结论 骨髓纤维化可致门脉高压 ,其特点是肝功能基本正常 。
Objective To study the specialities of myelofibrosis induced portal hypertension.Methods Six myelofibrosis patients diagnosed by bone marrow puncture and biopsy underwent gastroscopy,CT scan and liver function tests.Ten cases of liver cirrhosis were as the control.Results The 6 patients had nearly normal liver function tests,high white blood cell and platelet counts.There was massive fiber hyperplasia on the bone marrow biopsy.All 6 cases had esophageal varices on gastroscopy and diffuse hepatic lesion,portal vein enlargement and splenomegaly on CT scan and B mode ultrasound.The mea n portal pressure was 32±2cmH 2O measured with heart/liver radioactivity ratio.Conclusions Myelofibrosis can induce portal hypertention and with the specialities of nearly normal liver founction,splenomegaly and no hypersplenism.
出处
《北京医学》
CAS
北大核心
2000年第5期267-269,共3页
Beijing Medical Journal
