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高压氧治疗对颅脑损伤患者C-反应蛋白和血糖影响的临床研究 被引量:7

Clinical study on influence of hyperbaric oxygen therapy on blood levels of C reactive protein and glucose in patients with traumatic brain injury
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摘要 目的探讨高压氧治疗对颅脑损伤患者C-反应蛋白和血糖的影响。方法选取2012年1~6月收治的颅脑损伤患者72例,随机分为对照组与治疗组,对照组给予常规治疗,治疗组在此基础上给予高压氧治疗,对比两组患者治疗前后的C-反应蛋白和血糖水平。结果治疗后,两组病例的C-反应蛋白均有所下降,治疗组的下降水平明显优于对照组(P<0.05)。治疗后第1 d、3 d、5 d、7 d,两组病例的血糖均逐渐下降,但是治疗组的下降水平明显优于对照组(P<0.05),差异具有统计学意义。结论应用高压氧治疗颅脑损伤,对于降低患者的C-反应蛋白与空腹血糖具有理想的作用,有利于保持患者生命体征的稳定,能促进神经功能修复,改善预后,降低致残率和病死率。 Objective To explore the effect of hyperbaric oxygen therapy on blood levels of C - reactive protein and glucose in patients with traumatic brain injury. Methods Seventy two patients with craniocerebral injury treated in this hospital during January to June, 2012 were randomly divided into control group and trial group, patients in control group were given with routine treatment, and patients in trial group were given with hyperbaric oxygen therapy on the basis of routine treatment, and blood levels of C reactive protein and glucose were compared between these two groups before and after treatment. Results The blood level of C - reactive protein was decreased in these two groups after treatment, the degree of decrease in patients of trial group was significantly lower than that of patients in control group, and their difference was statistically signif- icant ( P 〈 0.05 ). The blood level of glucose in patients of these 2 groups was gradually decreased after treatment for 1, 3,5 and 7 days, but the degree of decrease in patients of trial group was significantly better than that of patients in control group, and their difference was statistically signif- icant ( P 〈 0.05 ). Conclusion The application of hyperbaric oxygen therapy in patients with traumatic craniocerebral injury had ideal effect of lowering the blood levels of C - reactive protein and fasting glucose, it is helpful in keeping the vital signs of patients in stable condition, and it can promote the recovery of neural function and improve the prognosis and reduce the rates of disability and mortality.
出处 《临床和实验医学杂志》 2013年第5期349-350,共2页 Journal of Clinical and Experimental Medicine
关键词 颅脑损伤 高压氧 C-反应蛋白 血糖 Traumatic brain injury Hyperbaric oxygen C -reaction protein Blood glucose
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