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脂联素与冠心病类型及心血管病危险因素的关系

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摘要 目的明确脂联素(APN)水平高低与冠心病(CHD)的类型和心血管病危险因素的关系,探讨APN水平是否会引起CHD,为冠心病的防治和预后提供临床参考。方法将115例患者随机分为3组,分别是对照组(CO)、稳定型心绞痛组(SAP)和急性冠状动脉综合征组(ACS)。将3组进行对比,研究CHD患者的APN水平,比较不同类型患者的APN水平以确定APN水平与CHD类型间的关系。经Logistic回归分析确定APN水平低是否会引起CHD。比较合并某一心血管病患者的APN水平和不合并者患者的APN水平间的差异。结果 APN水平低、高胆固醇是导致CHD的独立危险因素。体重超标、血脂不正常、吸烟、男性合并3个或3个以上危险因素的CHD患者APN水平降低,高血压和糖尿病合并患者APN水平变化不大。结论患有CHD后APN水平降低,患有ACS的患者比患有SAP的患者APN水平更低。APN水平低是导致CHD的危险因素。体重超标、血脂不正常、吸烟、男性会导致APN水平降低,合并患有心血管病等危险因素多的APN水平更低。
作者 程晓丹
出处 《当代医学》 2013年第9期40-41,共2页 Contemporary Medicine
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参考文献3

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