摘要
目的探讨小剂量131I治疗甲状腺功能亢进(甲亢)的临床疗效和副作用的发生情况。方法选择2009年5月～2011年12月经131I治疗并有复诊记录的甲亢患者124例,根据患者的症状、体征,每3个月口服1次131I1.5～2.5mci并检测甲状腺激素水平,直至甲亢症状、体征好转、甲状腺激素水平正常停药。结果治疗后随访1年以上,124例中,治愈114例,治愈率为91.9%;不同病程、甲状腺肿大程度、突眼的患者之间治愈率差异无统计学意义;14例出现一过性甲状腺功能减低,发生率为11.3%;4例复发,复发率为3.2%;未出现粒细胞减少、甲状腺危象等严重不良反应。结论小剂量131I治疗甲亢是一种经济、有效、安全、简便的治疗方法。
Objective To investigate the therapeutic effect and side effect on hyperthyroidism with small dosage 131I. Methods The dosage of 131I was from 1.5mci to 2.5mci based on the patient’s symptom and signs. Patients took 131I one time per 3 months until being cured. Results After one year’s follow-up, 114 cases were cured and the cure rate was 91.9%. The incidence rate of hypothyroidism was 11.3%. The recurrence rate was 3.2%. There weren’t any serious adverse reactions. Conclusion The method with small dosage 131I on hyperthyroidism is economic, effective, safe and simple.
出处
《当代医学》
2013年第8期145-146,共2页
Contemporary Medicine
