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急性重型颅脑疾病应激反应期亚低温对促肾上腺皮质激素分泌的影响 被引量:3

The influences on secreting ACTH in stress period of acute serious craniocerebral disease in sub-hypothermia
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摘要 目的研究在急性重型颅脑疾病 (急性重型颅脑损伤及重型高血压脑出血 )应激反应期中亚低温治疗对ACTH分泌的影响。方法采用北京康乐公司生产直冷式亚低温治疗仪 ,病人平躺在冰毯上 ,仪器控制其内循环水温使肛温维持在 32℃~ 35℃。选出观察组和对照组各 2 0例急性重型颅脑疾病病人 ,分别在入院当时和住院后第 1天、第 3天、第 7天测量血液中的ACTH分泌量 (观察组入院当时抽血后即行亚低温治疗 ) ,观察病人应激反应时上消化道出血和高血压发生及治疗情况。结果亚低温治疗组病人的ACTH水平明显低于对照组 ,上消化道出血病例较对照组少 ,高血压症状、体征轻于对照组 ,预后也较好。结论亚低温治疗能降低急性重型颅脑疾病患者ACTH分泌 ,有利于上消化道出血及高血压等并发症的治疗。 Objective [WT5”BZ]To study the influencse of sub-hypothermia to secrete ACTH in stress period of acute serious craniocerebral disease.Methods The direct-refigerate sub-hypothermia apparatus was used that controlling the temperature of circular water in the cooblanket patients lying on.The patients'anus temperature were controlled in the range of 32~35℃.40 patients suffering craniocerebral disease were divided into two groups that each group for 20 patients.The ACTH of blood were observed on the time being hospitalized,the first day,the third day and the seventh day respectively(after doing it the sub-hypothermia apparatus was used in the experience group).During those days,curative effect,stress ulcer and hypertension in acute reaction period were observed.[WT5”HZ]Results [WT5”BZ]Secreting ACTH in the experience group using sub-hypothermia apparatus were obviously lower than that in the control group.The symptoms and signs of stress ulcer ulcer and hypertension in the experience group were milder than in the control group.Moreover,the prognosis was going on well.Conclusion ACTH level of patients that suffering acute serious craniocerebral disease were reduced by the sub-hypothermia treatment.It was available for treatment and prevention of the complication.
出处 《贵州医药》 CAS 2000年第10期591-592,共2页 Guizhou Medical Journal
关键词 急性重型颅脑损伤 亚低温 ACTH 高血压脑出血 WT5”BZ]Sub-hypothermia Craniocerebral injury ACTH
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  • 1上海第一医学院.人体生理学[M].北京:人民卫生出版社,1979.615.

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