摘要
目的探讨综合性睡眠诱导对难治性肠易激综合征(IBS)患者身心状态的影响。方法将68例经常规治疗无效的IBS患者随机分成对照组和观察组各34例。两组均行抗焦虑抑郁及对症治疗,在此基础上对照组行常规护理,观察组实施综合性睡眠诱导。分别于干预前、干预3个月和6个月时进行焦虑、抑郁评定和消化道症状评定。结果两组焦虑、抑郁评分比较,干预主效应、时间效应及交互效应均P<0.01,干预6个月时IBS消化道症状治疗效果显著优于对照组(P<0.05)。结论采用综合性睡眠诱导辅助治疗难治性IBS能改善患者睡眠,缓解其焦虑抑郁情绪,提高治疗效果。
Objective To explore the effect of sleep induction on psychosomatic disorders in patients with refractory irritable bowel syndrome （IBS）. Methods Totally, 68 patients with refractory IBS who failed to respond to routine treatment were randomly and commensurately divided into a control group and an observation group. Both group received antidepressant therapy, anti-anxiety medications and symptomatic treatment. Besides those, the observation group additionally received sleep induction therapy. Before treatment,at 3 months and 6 months of treatment, levels of anxiety and depression, and gastrointestinal symptoms in all patients were assessed. Results The anxiety and depression scores had signifiacnt group effect, time effect and interaction effect between the 2 groups （P〈0.01 for all）. The gastrointestinal symptoms of the observation group were alleviated significantly at 6 months than the control group （P〈0.05）. Conclusion Sleep induction as an adjuvant therapy for patients with refractory IBS,not only improves their sleep quality,alleviates levels of anxiety and depression, but also enhances the effect of routine treatment.
关键词
难治性肠易激综合征
睡眠诱导
临床症状
焦虑
抑郁
消化道症状
refractory irritable bowel syndrome
sleep induction
clinical manifestation
anxiety
depression
gastrointesti- nal symptoms
