摘要
反义寡核苷酸包括反义RNA、反义DNA和Ribozyme。它能特异地拮抗内源或外源基因的表达 ,这为研究某特定基因功能提供了更为有效的方法 ,为培育抗病植株、调控次生代谢和农艺性状改良提供了可能途径。通过特定的化学修饰 。
Antisense oligonucleotide(ASON) includes antisense RNA, antisense DNA and Ribozyme. It can inhibit endogenote and exogenote expression particularly which provides a effective method for studying the faction of a certain specific gene and provides a possible pathway to breeding disease-resistence plants, modulating and controlling secondary metabolism, modifying agricultural character. The physical and chemical properities of ASON be changed via specific chemical modification, and thus enhencing ASON's antivirus as well as other specific gene expression inhibition activities.
出处
《黑龙江农垦师专学报》
2000年第3期82-85,共4页
Journal of Heilongjiang Nongken Normal College
