摘要
【目的】探讨内镜下逆行胰胆管造影（ERcP）术后并发胰腺炎的相关危险因素。【方法】回顾性分析本院1356例行ERCP患者的有关，临床资料。探讨术中静脉麻醉、胰管显影、胆管插管失败、内镜括约肌切开术（EST）、ERCP操作时问、胆管扩张、怀疑括约肌功能障碍、胆总管结石、年龄、黄疸、ERCP术后胰腺炎病史、高血压、糖尿病等方面的可能危险因素。【结果】胰管显影、胆管插管失败、EST、ERCP操作时间延长、无黄疸、ERCP术后胰腺炎病史、年龄及怀疑括约肌功能障碍均使ERCP后胰腺炎发生率升高（P〈0．05），而术中静脉麻醉、胆管扩张、高血压、糖尿病均未明显影响行ERCP后胰腺炎发生率（P〉0．05）。【结论】行ERCP后胰腺炎危险因素众多。其中，胰管显影、胆管插管失败、EST、ERCP操作时间延长、无黄疸、ERCP术后胰腺炎病史、年龄及怀疑括约肌功能障碍均为ERCP后胰腺炎的高危因素，而术中静脉麻醉、胆管扩张、高血压、糖尿病等不是ERCP后胰腺炎的高危因素。
[ObjectiveITo explore the related risk facts of the incidence of post-endoscopic retrograde cholangiopanereatography（ERCP） panereatitis. [Methods] The clinical data of 1356 patients undergoing ER- CP in our hospital were analyzed retrospectively. The possible risk factors such as intraoperative intravenous anesthesia, pancreatic duet developing, cystic duct cannula failure, endoscopic sphincterotomy（EST）, ERCP operation time, cholangiectasis, suspected sphincter dysfunction, age, jaundice, pancreatitis history after ER- CP, hypertension, diabetes and so on were discussed. [Results] Pancreatic duet developing, cystic duct can- nula failure, EST, long ERCP operation timfi, no-jaundice, pancreatitis history after ERCP, age and suspected sphincter dysfunction increased the incidence of post-ERCP panereatitis （ P 〈0. 05）. The incidence rate of post-ERCP panereatitis was not obviously affected by intravenous anesthesia, cholangiectasis, hypertension and diabetes（ P 〉0. 05）. [Conclusion] There are many risk factors of post-ERCP pancreatitis. Pancreatic duct developing, cystic duct cannula failure, EST, long ERCP operation time, no-jaundice, pancreatitis histo- ry after ERCP, age and suspected sphincter dysfunction are high risk factors of post-ERCP pancreatitis, but intravenous anesthesia, cholangiectasis, hypertension and diabetes are not the risk factors of post-ERCP pan- creatitis.
出处
《医学临床研究》
CAS
2013年第2期297-300,共4页
Journal of Clinical Research
关键词
胰腺炎
病因学
危险因素
胰胆管造影术
内窥镜逆行
pancreatitis /ET
risk factors cholangiopancreatography, endoscopic retrograde
