摘要
目的探讨恶性上皮卵巢肿瘤发生的影响因素。［方法］应用１：１配对病例对照研究，收集３所医院妇科收治的恶 性上皮性卵巢肿瘤患者５２例作为病例组，收集同期住院的非妇产科、非肿瘤、与激素无关的其他女性患者５２例作为对照组，两组 间同性别、同民族、一对内年龄相差不过５岁，对所得资料进行单因素条件Ｌｏｇｉｓｔｉｃ回归分析及多元条件Ｌｏｇｉｓｔｉｃ回归分析。［结果］ 有恶性肿瘤家族史、暴露于滑石粉为上皮性卵巢癌主要的危险因素，而多产、哺乳为主要的保护因素；高促性腺激素水平及低雄 激素水平可能与上皮性卵巢癌的危险增加有关。［结论］恶性上皮性卵巢肿瘤可能为多种因素综合作用的结果，既与环境因素有 关，又与遗传因素、生殖因素和内分泌因素有关。
Purpose To investigate related etiologic factors of ovarian carcinoma. [Methods] As1: 1 matching case-control study was carried out. Fifty-two pathologically proved and an equal number of control were collected from three hospitals. The data were analyzed by conditional logistic regression. [Results] Family history of malignant tumors and talc exposure were risk factors for ovarian carcinoma and breast-feeding were protective factors for the disease High gonadotropin levels and low androgen levels might increase risk of ovarian carcinoma. [Conclusion] The etiology of ovarian carcinoma is probably multifactors such as reproduction, environment and hormon.
出处
《中国肿瘤》
CAS
2000年第7期327-328,共2页
China Cancer
关键词
恶性上皮性卵巢肿瘤
病因学
危险因素
Ovarian neoplasms Etiology Risk factors Case-control study
