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对AgNOR用于宫内膜病变诊断的评价

DIAGNOSIS OF THE ENDOMETRIAL DISEASES WITH AgNOR
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摘要 目的 寻找一种有助于对宫内膜不同性质病变进行诊断和鉴别诊断的客观指标。方法 用核仁组成区银染法显示核仁组成区嗜银蛋白 (AgNOR) ,对增生期宫内膜、内膜增生过长、内膜癌等 3组 (6 0例 )不同性质病变进行观察对照并记数。结果  3组间差别明显。内膜癌组细胞AgNOR颗粒均数 2 7.0 9,增生过长组AgNOR颗粒均值16 .6 2 ,增生期宫内膜AgNOR颗粒均值 10 .2 4,各组间P <0 .0 1,具有统计学意义。组间AgNOR颗粒大小、形态、分布亦有区别。结论 AgNOR法观察指标客观 ,对不同性质的宫内膜病变诊断和鉴别诊断有一定价值。 three ential diagnosis method were used among three endometrial diseases,e.g.hyperplasia endometrium(HE),endmoetrial hyperplasia(EH) and endometrial adenocarcinoma(EA)(n=60).The results showed that the AgNOR number of EA was the most among three groups,EH in middle and HE was the least,showing significant difference(P<0.01) only in endometrial adenocarinoma (EA) group.AgNOR size,shape and distribution changed greatly.It suggested that the number,the size and the shape of AgNOR may be a good indicator for diagnosis.
出处 《青海医学院学报》 2000年第3期1-2,共2页 Journal of Qinghai Medical College
关键词 AGNOR 增生期宫内膜 内膜增生过长 子宫内膜癌 AgNOR hyperplasia endometrium(HE) endometrial hyperplasia(EH) endometrial adenocarcinoma(EA)
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  • 1D. Ploton,M. Menager,P. Jeannesson,G. Himber,F. Pigeon,J. J. Adnet. Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region at the optical level[J] 1986,The Histochemical Journal(1):5~14
  • 2周晓军,黄进,喻毅强,张太和.胃癌核仁组成区相关蛋白的研究[J].江苏医药,1990,16(2):68-69. 被引量:4

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