摘要
目的分析呼吸科普通病房和呼吸重症加强治疗病房(RICU)住院患者下呼吸道感染病原菌分布和药敏的差异。方法对呼吸科普通病房和RICU下呼吸道感染住院患者痰菌(或纤支镜吸取分泌物)培养阳性结果进行回顾性统计分析。结果共分离出菌株3202株。其中普通病房1254株,革兰阳性菌2.63%,革兰阴性菌42.42%,真菌54.95%。革兰阳性菌中,以肺炎链球菌为主,占51.52%;革兰阴性菌中,以副流感嗜血杆菌居首位,占21.99%,二者均对大多数常用抗菌药物敏感。RICU分离的1948株病原菌中,革兰阳性球菌4.52%,革兰阴性杆菌37.73%,真菌57.75%。革兰阳性菌中,以金黄色葡萄球菌居为主,占52.27%,革兰阴性菌中,以鲍曼不动杆菌居首位,占27.35%,二者均对大多数常用抗菌药物耐药。铜绿假单胞菌无论是在普通病房还是RICU均有较高感染率,且对大多数常用抗菌药物耐药。结论呼吸科普通病房革兰阳性菌感染中以肺炎链球菌为主,革兰阴性菌感染以副流感嗜血杆菌为主,二者均对大多数常用抗菌药物敏感;RICU革兰阳性菌感染中以金黄色葡萄球菌为主,革兰阴性菌感染以鲍曼不动杆菌为主,二者均对大多数常用抗菌药物耐药。
Objective To investigate the differences in bacteria distribution and drug resistance of pathogens in patients with lower respiratory tract infection between respiratory general wards and respiratory intensive care unit （RICU）. Methods All the clinical isolates from sputum or secretion of lower respiratory tract from 2007.1-2010.10 were analyzed retrospectively. Antibiotic susceptibility was tested by Kirby-Bauer method. Results The total number of isolated strains was 3202. Among 1254 strains isolated from respiratory general wards,Gram-positive bacteria accounted for 2.63% ,Gram-positive bacteria accounted for 42.42%, and fungi accounted for 54.95 %. Streptococcus pneumoniae ranked first place among Gram-positive bacteria,accounting for 51. 52%. Haemophilus parainfluenzae bacillus ranked first place among Gram- negative bacteria, accounting for 21.99%. Both were sensitive to the most commonly used antibiotics. Among 1948 strains isolated from RICU ward, Gram-positive bacteria accounted for 4.52%, Gram-positive bacteria accounted for 37.73% ,and fungi accounted for 57.75%. Staphylococcus aureus ranked first place among Gram-positive bacteria,accounting for 52.27%. Acinetobacter baumannii ranked first place in Gram- negative bacteria, accounting for 27. 35%. Both were resistant to most commonly used antibiotics. Pseudomonus aeruginosa had a higher rate of infection both in the general wards and RICU ,and was resistant to most commonly used antibiotics. Conclusions In lower respiratory tract infection of respiratory general ward, Gram-positive bacteria with Streptococcus pneumoniae mainly and Gram-negative bacteria with Haemophilus parainfluenzae mainly are both sensitive to the most commonly used antibiotics. While in theRICU ward, Gram-positive bacteria infections with Staphylococcus aureus mainly and Gram-negative bacteria infections with Acinetobacter baumannii mainly are both resistant to most commonly used antibiotics.
出处
《中国呼吸与危重监护杂志》
CAS
2013年第2期124-128,共5页
Chinese Journal of Respiratory and Critical Care Medicine
关键词
下呼吸道感染
药敏
抗菌药物
呼吸重症加强治疗病房
普通病房
Lower respiratory tract infection
Drug resisitance
Antibacterials
Respiratoryintensive care unit
General wards
