摘要
目的研究米非司酮联合甲氨蝶呤治疗宫外孕的疗效和不良反应,探讨其临床应用价值。方法回顾分析2010年5月至2012年5月间105例宫外孕患者的临床资料,其中甲氨蝶呤治疗51例(对照组),米非司酮联合甲氨蝶呤治疗54例(治疗组),比较两组疗效和不良反应。结果对照组和治疗组有效率分别是74.51%和81.48%,治疗组疗效高于对照组(P<0.05);对照组和治疗组不良反应发生率分别是11.76%和12.96%,差异无统计学意义(P>0.05)。结论米非司酮联合甲氨蝶呤治疗宫外孕疗效确切,值得临床推广。
Objective To investigate the effect of mifepristone combine with methotrexate in treating ectopic pregnancy. Methods The clinical data of 105 patients with ectopic pregnancy between May 2010 and May 2012 were analyzed. Among them, 51 cases treated by methotrexate （control group）, and 54 cases treated by mifepristone combine with methotrexate （treat group）, then the effects and complication was observed. Results The effective power in treat group and control group were 74. 51% and 81.48% espectively. And the effective power in treat group was higher than that in control group（P 〈 0. 05）. The complication in treat group and control group were 11.76% and 12.96% espectively. And there was no statistically significant between two groups（P 〉 0.05）. Conclusion The combination of mifepristone with methotrexate is effective for treating ectopic pregnancy.
出处
《中国药业》
CAS
2013年第5期91-92,共2页
China Pharmaceuticals
关键词
宫外孕
米非司酮
甲氨蝶呤
ectopic pregnancy
mifepristone
methotrexate
