摘要
Arrestins是继G 蛋白偶联受体激酶 (GRK)之后发现的另一个中介受体脱敏的重要可溶性蛋白。它不仅在受体脱敏 ,而且在受体胞吞 ,内部化 。
Arrestin is an important soluble protein that mediates receptor desensitization which is found after G protein coupled receptor kinase(GRK).It plays an important role not only in receptor desensitization,but also in receptor endocytosis, internalization, resensitization and mitogenic signaling.
出处
《中国药理学通报》
CAS
CSCD
北大核心
2000年第4期377-380,共4页
Chinese Pharmacological Bulletin
基金
国家自然科学基金资助课题 !No 395 70 82 7
关键词
G-蛋白偶联受体激酶
ARRESTINS
受体脱敏
receptor desensitization
receptor resensitization
receptor internalization
mitogenic signaling
