摘要
目的研究中国成人腰围身高比(WHtR)与血脂异常的关系,并提出WHtR预测血脂异常的适宜截点。方法采用整群随机抽样,对2008至2009年度在4个全国性体检机构进行健康查体的221270名城市人群,测量其身高、体重、腰围(WC),计算体质指数(BMI)和WHtR,并检测血脂四项。采用受试者工作特征曲线(ROC)比较曲线下面积,计算不同水平肥胖指标预测血脂异常的灵敏度和特异度,通过约登指数最大值找到适宜截点。结果WHtR在高TC血症、高TG血症及高LDL—C血症的ROC曲线下面积最大,其次为WC及BMI;WHtR最佳截点范围男性为0.49~0.50,女性为0.47~0.49;WC男性为83~85enl,女性为73~76em;BMI男性为24~25kg/m^2,女性为22~23kg/m^2。结论WHtR筛查不同类型的血脂异常优于WC和BMI,推荐适宜截点男女性均为0.5。
Objective To explore the association between waist-to-height ratio (WHtR) and dyslipidemia in Chinese adults and to find out an optimal threshold of WHtR for predicting dyslipidemia. Methods A total of 221 270 adults from 4 health checkup centers nationwide were selected by using cluster random sampling method. Height, body weight, waist circumference ( WC ) , total cholesterol ( TC ), triglyceride ( TG ), high-density lipoprotein cholesterol ( HDL-C ) and low-density lipoprotein cholesterol(LDL-C) were measured. Body mass index (BMI) and WHtR were then calculated. The area under the receiver operating characteristic curve( AUC ) was analyzed and optimal cutoffs were estimated by maximizing the sums of sensitivity and specificity. Results WHtR showed the largest AUCs in the participants with higher TC, TG and LDL-C, followed by increased WC and BMI. In male and female, the optimal thresholds of WHtR, WC and BMI for predicting dysfipidemia were 0.49-0. 50 and 0. 47-0. 49,83-85 and 73-76 cm, and 24-25 and 22-23 kg/m^2, respectively. Conclusion WHtR may be superior to WC and BMI for predicting dyslipidemia, and an unisex cutoff of 0. 5 should be recommended.
出处
《中华健康管理学杂志》
CAS
2013年第1期9-13,共5页
Chinese Journal of Health Management
基金
国家“十二五”科技支撑计划(2012BA137B04)志谢感谢解放军总医院国际医学中心、国际白求恩和平医院健康管理中心、中南大学湘雅三院健康管理中心、第三军医大学西南医院体检中心所有现场工作人员的辛勤工作,感谢所有调查对象的支持.
关键词
血脂异常
成年人
身高
Dyslipidemias
Adult
Body height