摘要
目的探讨老年男性血清25羟维生素D水平对于心脏左心室肥厚(LVH)的预测意义。方法选取333例老年男性患者,根据是否合并LVH分为非LVH组208例,LVH组125例,2组行超声心动检查,采用ELISA法检测血清25羟维生素D,采用多因素多元逐步回归分析。结果与非LVH组比较,LVH组血清肌酐水平明显升高,差异有统计学意义(P<0.05);血清25羟维生素D明显降低[(35.5±14.8)nmol/L vs(30.7±10.8)nmol/L,P<0.05],左心室重量指数(LVMI)明显增高(P<0.01)。体重指数和25羟维生素D与LVMI独立相关(β=0.216,-0.155,P<0.01)。结论在老年男性患者中,较低的25羟维生素D水平可能是LVH的独立危险因素。
Objective To study the correlation between serum 25-hydroxyvitamin D level and left ventricular hypertrophy（LVH） in elderly males. Methods Three hundred and thirty-three elderly males were divided into non-LVH group（n=208） and LVH group（n=125） and underwent ultrasonography. Their serum 25-hydroxyvitamin D level was measured by ELISA and analyzed by multivariate stepwise linear regression analysis. Results The serum creatinine level was significantly higher in LVH group than in non-LVH group（P〈0.05）. The serum 25-hydroxyvitamin D level was significantly lower in LVH group than in non-LVH group（30. 7±10. 8 nmol/L vs 35.5±14.8 nmol/L,P〈0.05）. The left ventricular mass index（LVMI） was significant higher in LVH group than in non-LVH group（P（0.01）. The body weight index and serum 25-hydroxyvi tamin D level were independently correlated with the LVMI（P〈0.01）. Conclusion Low serum 25-hydroxyvitamin D level is an independent risk factor for LVH in elderly males.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2013年第3期262-264,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
