摘要
目的探讨单纯疱疹病毒(HSV)感染的血清学指标检测的临床价值,为临床诊治提供依据。方法采用酶联免疫吸附法检测251例典型症状患者、78例无症状可疑患者、63例健康查体者HSV-2IgM/IgG。结果典型症状者、无症状可疑者和健康查体者IgM阳性率分别为90.8%、32.1%和3.2%,IgG阳性率分别为97.6%、35.9%和4.8%;典型症状者IgM、IgG阳性率明显高于无症状可疑者和健康查体者(P<0.05);无症状可疑者IgM、IgG阳性率明显高于健康查体者,差异有统计学意义(P<0.05)。结论血清HSV抗体不仅在典型症状者升高,而且能检出无症状的感染者,可为临床HSV感染的诊断及流行病学研究提供重要依据。
OBJECTIVE To discuss the clinical value of serum indexes in detection of herpes simplex virus（HSV） infections so as to provide basis for the clinical diagnosis and treatment. METHODS HSV-2 IgM/IgG were detected in 251 cases of patients with typical symptoms, 78 cases of asymptomatic suspected patients, 63 cases of healthy people by enzyme-linked immunosorhent assay. RESULTS The positive rates of IgM of the typical symptom patients, asymptomatic suspected patients and healthy people were 90.8%, 32.1 % and 3.2%, respectively, the positive rates of IgG were 97. 6%, 35. 9% and 4. 8%, respectively. The positive rates of IgM and IgG of the typical symptom patients were significantly higher than those of the asymptomatic suspected patients and the healthy people（P〈0. 05）. The positive rates of IgM and IgG of the asymptomatic suspected patients were significantly higher than those of the healthy people, the difference was statistically significant （P 〈 0. 05）. CONCLUSION The level of serum HSV antibody is not only elevated in the typical symptoms patients but also in the asymptomatic suspected patients, which can provide a reliable basis for the clinical diagnosis of HSV infection as well as for the epidemiological study.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第6期1476-1477,共2页
Chinese Journal of Nosocomiology
