摘要
目的了解潍坊市健康人群麻疹、风疹、流行性腮腺炎血清抗体水平,为消除麻疹、控制风疹及腮腺炎疫情提供依据。方法 2011年8月,采集昌乐、潍城2个县区<2、2～5、5～8、8～11、11～15、15～20、20～40、>40岁健康人群血标本,应用酶联免疫吸附试验检测麻疹、风疹、腮腺炎IgG抗体。结果检测总数320人,其中昌乐县健康人群的麻疹抗体阳性率为98.75%、潍城为96.25%;风疹抗体阳性率昌乐县健康人群为89.38%、潍城区为91.88%。昌乐、潍城两地区健康人群麻疹、风疹的抗体阳性率差异均无统计学意义(χ2=1.15、0.59,P>0.05);昌乐县健康人群腮腺炎抗体阳性率为84.38%、潍城区健康人群为66.25%,两者差异有统计学意义(χ2=14.14,P<0.01);8组不同年龄健康人群的麻疹抗体阳性率为92.50%～100%,风疹抗体阳性率为87.50%～92.50%,腮腺炎抗体阳性率为67.50%～85.00%,各年龄组间均无统计学意义(χ2=13.49、1.58、5.23,P>0.05)。结论潍坊市麻疹抗体阳性率较高,风疹、腮腺炎抗体阳性率相对偏低,今后须要积极开展学龄儿童麻腮风三联疫苗的查漏补种工作。
Objective To know the antibody level of measles, rubella and mumps among the normal healthy persons in Weifang city, to provide the evidences for eliminating measles and controlling rubella and mumps outbreaks. Methods The serum specimens were collected from the hehhy persons of the different age groups, and the IgG antibody levels against measles, rubella and mumps were detected by ELISA. Results A total of 320 samples were detected, the positive rate of measles antibody is 98.75% and, 96.25% in Changle county and Weicheng district, respectively; the positive rate of rublla antibody is 89.38 % and 91.88% respectively, there is not statistical difference of measles and rublla antibody positive rate between Changle and Weicheng （χ^2 = 1.15, 0.59, P〉0.05 ） ; the positive rate of mumps antibody in Changle county is 84.38 %, wereas the positive rate is 66.25% in Weicheng, there is statistical difference of positive rate between two areas （χ^2 = 14.14, P〈0.01 ） ; The range of measles antibody positive rate is 92.50%-100% ; the range of rubella antibody positive rate is 87.50%-92.50% ; the range of mumps antibody positive rate is 67.50%-85.00%. There is not significance in the different age groups （χ^2 = 13.49, 1.58, 5.23, P〉0.05 }. Conclusions The measles IgG antibody level is high in Weifang city, but the rubella and mumps IgG antibody level is lower. It is necessary to perform the work of checking leak and supplemental vaccinating vaccine in the school-age children.
出处
《微生物学免疫学进展》
2013年第1期52-54,共3页
Progress In Microbiology and Immunology
