摘要
掌握百色市乙型肝炎疫苗纳入儿童免疫规划后的免疫效果,客观评价免疫规划工作现状。方法按现况研究原理,全市12个县(区),每个县(区)各抽取150名儿童,每个县在东、西、南、北、中五个方位随机抽取5个行政村,每个行政村抽取6个年龄组(1～6岁儿童),每个年龄组抽取5名常住儿童(当地居住三个月以上),收集血清样本进行乙肝病毒感染相关标志表面抗原及抗体检测。结果全市共调查1～6岁儿童1 809名儿童,乙肝表面抗原携带率为0.66%,低于2006年全国调查的1～4岁人群乙肝表面抗原携带率(0.96%),达到中国《2006—2010年全国乙型病毒性肝炎防治规划》提出的5岁以下儿童乙肝表面抗原携带率<1%的控制目标要求;1～6岁儿童乙肝表面抗体阳性率为77.77%,高于2006年全国调查的1～4岁人群乙肝抗体阳性率(71.24%)。结论百色市自2003年将乙肝疫苗纳入免疫规划管理后,乙肝免疫效果显著,乙肝病毒表面抗原阳性率大幅度下降,婴幼儿体内保护性抗体水平也高于全国水平。加强对孕产妇住院分娩率和婴幼儿乙肝疫苗接种工作,尤其是乙肝疫苗首针及时接种是今后乙肝预防控制的重点。
Objective To evaluate the quality and effort of immunization after Hepatitis B vaccine introduced into EPI in Baise city. Methods This survey was carried out in the 12 counties of the Baise city, 5 villages were selected from different locations of each county,in every country 150 children （ 1-6 years old） were selected to collect blood serum and to detect the HBsAg and anti-HBs. Results 1 809 children＇ s blood serum samples were detected in the laboratory. The positive rate of the HBsAg was 0.66 %, lower than that of the survey （ 0.96 % ） in 2006. The positive rate of the anti-HBs was 77.77 %. higher than that of the survey（71.24% ） in 2006. Conclusion After being brought into the EPI, the HBV＇ s coverage rate was enhanced year by year. The rate of the HB carrier declined greatly, and the positive rate of the anti-HBs in Baise city was higher than that of the level of the country. To promote the coverage of immunization, in particular, performing the first dose timely should be the priority of our work in the future.
出处
《微生物学免疫学进展》
2013年第1期16-19,共4页
Progress In Microbiology and Immunology
