摘要
目的探讨Isaacs综合征临床表现、肌电图特点及临床转归。方法分析5例神经性肌强直病例的临床症候、肌电图表现、诊断及治疗情况,并进行文献回顾。结果 5例病例临床主要表现为肌肉颤搐、多汗等;肌电图表现为持续快速的二联、三联或多联的运动单位放电活动;应用卡马西平可缓解临床症状。结论神经性肌强直是一种少见的周围神经病变,自发性连续性肌肉活动为其主要表现;肌电图特点为持续快速的二联、三联或多联运动单位放点活动;应用卡马西平治疗有效,但仍需定期随访。
Objective To evaluate clinical manifestation, characteristic eleetromyography and prognosis of Isaaes' syndrome. Methods Clinical data, characteristic electromyography, diagnosis and treatment of five cases with Isaacs' syn- drome were analyzed retrospectively while making a literature review. Results Five cases' clinical manifestation were myok- ymia and hyperhidrosis. Electromyography show typical bigeminy, trigeminy and multigeminy motor unit discharge. Carbamaz- epine could relieve most of clinical symptoms. Conclusion Isaacs ' syndrome is a rare peripheral nerves disease. The sponta- neous and consecutive museulation is main clinical manifestation. Electromyography show typical bigeminy, trigeminy and mul- tigeminy motor unit discharge. Carbamazepine is preferred drugs for Isaaes' syndrome. Regular following-up is necessary.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
2013年第2期154-156,共3页
Journal of Apoplexy and Nervous Diseases