摘要
目的探讨髓母细胞瘤的影像表现及临床治疗方法。方法回顾性分析29例经术后病理证实为髓母细胞瘤病人的影像学资料、治疗方法及预后。结果 29例髓母细胞瘤均位于小脑蚓部近中线处,均以实质性为主。MRI表现T1像呈稍低信号,T2像呈稍高信号,Flair像呈稍高信号,囊变坏死区呈长T1、长T2信号;增强扫描肿瘤实质多呈不同程度强化;19例肿瘤周围可见明显水肿,21例呈现不同程度的脑积水征象。所有病人均行显微手术治疗,肉眼全切者23例,大部切除者4例,少量切除者2例;术后29例均行放射治疗,15例同时行化疗。平均随访2.9年,生存率为69%。结论髓母细胞瘤具有较为典型的影像学特征,手术切除是目前首选治疗措施,放疗及化疗是术后主要的辅助治疗方法。
Objective To study imaging features and therapies of medulloblastomas （MB）. Methods A retrospective analysis was conducted for imaging data, therapies and prognosis of 29 patients with MB, their diagnosis was confirmed by posto perative pathology. Results All of the tumors were solid, locating at cerebellar vern, is near to the central line. MRI manifesta tions： slight hypointensity signal on TlW, slight hyperintensity on T2W and Flair, long T1 and T2 signal were seen in cystic and zone of necrosis. The parenchyma of 1he tumor showed different extent of enrichment after contrast enhancement. Obvious edema surrounding the tumor could be seen in 19 cases, different degree of hydrocephalus sign seen in 21. All of whom underwent micro- surgery. Total resection was done in 23 cases, subtotal in four, and small amount resection in two. Radiotherapy was offered to all the patients,l,5 of them received chemotherapy at the same time. An average follow up of 2.9 years showed the survival of 69%0. Conclusion Medulloblastomas have typical imaging features, surgical ablation is the first choice for this condition at present. Ra diotherapy and chemotherapy are principal postoperative adjunctive therapies.
出处
《齐鲁医学杂志》
2013年第1期30-32,共3页
Medical Journal of Qilu
关键词
髓母细胞瘤
体层摄影术
X线计算机
磁共振成像
治疗结果
medulloblastomas
tomography, X ray computed
magnetic resonance imaging
treatment outcome
