摘要
目的:探讨脑卒中后癫痫的发病机制、临床特点及预后。方法:采用流行病学分析方法,对本院脑卒中后癫痫33例患者临床资料进行回顾性分析。结果:脑卒中后癫痫发生率3.32%,其中早发性癫痫发生率0.2%,迟发性癫痫发生率3.30%。皮层病灶继发癫痫66.67%,皮层下病灶继发癫痫33.33%,两者比较,差异有统计学意义(P<0.05)。部分性发作8例(24.24%)。全身强直阵挛性发作22例和癫痫持续状态3例,占75.76%。出血性卒中继发癫痫占所有脑出血患者的9.62%,缺血性卒中继发癫痫占所有脑梗死患者的2.30%,两者比较差异有统计学意义(P<0.05)。2例早发性癫痫者,患者服药期间无再发作。31例迟发性癫痫患者,有3例偶再发作,1例患者联合应用两种抗癫痫药治疗不能有效控制发作。早发性癫痫与迟发性癫痫比较,疗效均较好,两者比较差异无统计学意义(P>0.05)。结论:脑卒中后癫痫以迟发性癫痫多见,皮层病灶较皮层下病灶易发生癫痫,以全面性发作为多见。出血性卒中易继发癫痫。脑卒中后癫痫疗效好。
Objectlve To analyze the pathogenesis, clinical features, treatment and prognosis of epilepsy following cerebral stroke sei- zure. Method The clinical data of 33 patients with epilepsy following cerebral stroke seizure in our hospital was analyzed retrospectively by epidemiological method. Results Among the all stroke patients,3.32% developed epilepsy. Among them,0. 2% developed seizures in early stage ,3.30% in late stage. 66. 67% % suffered seizures located in brain cortex while 33.33% % were located in sub - cortex,and the com- parison of both showed statistical difference （P 〈 0. 05）. The incidence of partial seizure was 24. 24%. Generalized tonic - clonic seizure （GTS） and status epilepticus occurred in 22 cases and 3 cases respectively, accounting for 75.76%. Hemorrhagic stroke secondary - onset epilepsy took up 9. 62% of all patients with cerebral hemorrhage, while ischemic stroke secondary - onset epilepsy took up 2. 30% of all pa- tients with cerebral infarction, and the comparison of the above - mentioned two showed statistical difference （ P 〈 0.05 ）. Two cases of the early - onset epilepsy patients did not break out again during the dose - taking period. Of the 31 cases of late - onset epilepsy patients ,3 ca- ses broke out occasionally. 1 patient,who was under the combined treatment of two anti -epilepsy medicines, could not control the outbreak effectively. In the comparison of early - onset epilepsy and late - onset epilepsy, the curative effects of both were good. The comparison of the two showed no statistical difference （P 〉 0. 05）. Conclusion In the case of epilepsy following cerebral stroke seizure,late -onset epi- lepsy is more common. Seizures located in brain subcortex are seen more commonly than seizures located in brain cortex, with generalized seizure commoner. Patients with hemorrhagic stroke are more liable to suffer secondary - onset epilepsy. The curative effects of the epilepsy following cerebral stroke seizure are good.
出处
《吉林医学》
CAS
2013年第4期609-611,共3页
Jilin Medical Journal
关键词
脑卒中
癫痫
脑梗死
脑出血
脑卒中后癫痫
Strok
Epilepsy
Cerebral infarction
Cerebral hemorrhage
Poststroke epilepsy
