摘要
目的:对比评价POCT法和化学发光法定量检测cTnI的检测效能和可靠性,并探讨POCT法Myo、CK-MB和cTnI三项联合定性检测对AMI患者早期诊断的价值。方法:收集60例患者,采用POCT法和化学发光法对cTnI进行测定,对结果进行比较和分析;并对42例早期入院病人在不同时点进行三项联合检测,比较敏感性。结果:在cTnI阴性和高浓度时,仅化学发光法能检测;在低和中浓度时两种方法之间没有统计学差异(P>0.05),但相关性很强;三项联合定性检测中Myo升高时间最快,敏感性高。结论:POCT法快速简便,适于快速诊断;化学发光法灵敏度高,特异性和准确性好,适于确诊和监测。
Objective：To evaluate and compare the clinical performance and reliability of POCT and chendh,mi- nescence method in the determination of troponin I, and to study the value of Myo - CK - MB - cTnI combined de- tection in early diagnosis for acute myocardial infarction （AMI） by POCT. Methods： Troponin I levels were detec- ted with both chemiluminescence and POCT methods in 60 patients. The results were compared and analyzed. And 42 cases of early stage patients were selected to carry out Myo - CK - MB - cTNI combined detection at diffcr~~t time, then to compare the sensitivity. Results： When the troponin I levels were ohviously low and high, results shown by two methods were significantly different, and only chemiluminescence could used for detection. While at low and mediate levels, troponin 1 showed no statistical difference between the two methods （P 〉 0.05） , bu! high linear correlation. Meanwhile, Myo showed the quickest rise and high sensitivity in combined detection. Conclu- sion： Being quick and simple, POCT is suitable for initial screening. Chemiluminescence is beneficial for the diag- nosis and monitoring because of its high sensitivity and good accuracy.
出处
《中国卫生检验杂志》
北大核心
2013年第2期392-394,共3页
Chinese Journal of Health Laboratory Technology
基金
杭州市医药卫生科技计划项目(20100633B17)
