摘要
目的:探讨血清白蛋白(ALB)、胆碱酯酶(CHE)、心肌酶TNT水平在多器官功能障碍综合症(MODS)的变化特点和预后的关系。方法:选取我院2010年1月至2012年6月的重症监护室收治的189例多器官功能障碍综合症(MODS)患者作为研究对象,同时选择同期重症监护室未出现多器官功能障碍综合症(MODS)患者30例作为对照研究,分别对其血清中的白蛋白,胆碱酯酶,肌钙蛋白T(TNT)进行测定,并分析其与患者预后的关系。结果:多器官功能障碍综合症(MODS)患者血清白蛋白、胆碱酯酶、肌钙蛋白T(TNT)水平与对照组比较其值有显著差异(P<0.01),多器官功能障碍综合征(MODS)患者中死亡组与非死亡组血清白蛋白、胆碱酯酶、肌钙蛋白T(TNT)水平比较有显著差异(P<0.01)。多器官功能障碍综合症(MODS)患者血清白蛋白、胆碱酯酶、明显降低,肌钙蛋白T(TNT)明显升高,未出现多器官功能障碍综合症(MODS)患者血清白蛋白及胆碱酯酶、肌钙蛋白T(TNT)变化不明显。患有多器官功能障碍综合征(MODS)患者中死亡的病例较未死亡的患者血清白蛋白、胆碱酯酶、降低明显,肌钙蛋白T(TNT)明显升高。结论:检测血清白蛋白及胆碱酯酶肌钙蛋白T(TNT)可作为MODS估计病情和评估预后的一项指标。血清白蛋白及胆碱酯酶越低和肌钙蛋白T(TNT)明显升高说明多器官功能障碍综合症(MODS)患者病情越重,预后越差。
Objective: To discuss the changes and relationship with prognosis of serum albumin ( ALB ) and cholinesterase (CHE), the level of cardiac enzymes TNT in multiple organ dysfunction syndrome (MODS) . Method:Selected the hospital from January 2010 to June 2012 the .intensive care unit admitted 189 cases of multiple organ dysfunction syndrome (MODS) patients as research subjects, at the same time, selected the same period in the intensive care unit does not appear in patients with multiple organ dysfunction syndrome ( MODS ) in 30 cases as a control, and respectively, were measured in its serum albumin, cholinesterase, serum creatine kinase TNT, and analyze its relationship with the prognosis of patients. Result:Compared with the control group, patients with multiple organ dysfunction syndrome ( MODS ) , their serum albu-min, cholinesterase, serum creatine kinase TNT level reduce significantly (P〈0.01), and the patients with multiple organ dysfunction syndrome ( MODS ) in the group of death and non-fatal serum albumin, cholines- terase, serum creatine kinase TNT levels reduce significantly. Conclusion:The detection of serum albumin and eholinesterase cardiac enzymes TiNT can be used as the the MODS estimated an indicator of disease and assessment of prognosis. The lower serum albumin and cholinesterase cardiac enzymes TNT multiple organ dysfunction syndrome ( MODS) in patients with more severe the disease, the worse the prognosis.
出处
《河北医学》
CAS
2013年第4期490-492,共3页
Hebei Medicine