摘要
目的探讨艾司洛尔对老年高血压冠心病患者诱导插管反应的影响。方法选择2010-02/2012-02收治的择期行全麻手术的高血压冠心病患者97例。随机将患者分为研究组45例和对照组42例。对照组患者采用丙泊酚,芬太尼,阿曲库铵进行麻醉诱导,研究组患者在对照组患者的基础上加用静注艾司洛尔。比较分析2组患者的一般临床资料以及麻醉诱导过程中心率、收缩压、舒张压以及平均动脉压的变化情况。结果 2组患者插管后心率、收缩压、舒张压以及平均动脉压均较插管前提高。与对照组患者相比,采用艾司洛尔的研究组患者插管后1 min、3 min及5 min的心率、收缩压、舒张压以及平均动脉压均明显降低,差别均具有统计学意义(P<0.05)。讨论艾司洛尔对高血压冠心病患者气管插管时引起的不良反应具有显著的预防作用,适于临床进一步广泛的推广使用。
Objective To probe into the effect of esmolol in induced intubation response for elderly hypertensive patients with coronary artery disease. Methods Selected February 2010 to February 2012, 97 elderly hypertensive patients with coronary heart disease in our hospital for elective anesthesia. The patients were divided into study group, which has 45 cases, and control group, which has 42 cases randomly. Control group were treated with propofol, fentanyl and atra- curium for the induction of anesthesia. While patients in study group used propofol, fentanyl atracurium and esmolol. Comparative analysis of the clinical data and HR, SBP, DBP, MAP changes during induction of anesthesia. Results HR, SBP, DBP and MAP of patients after intubation in two groups were increased. Compared with control group, the patients used esmoloI in study group lmin, 3rain and 5min after intubated, HR, SBP, DBP and MAP were significant- ly reduced, there was significant differences （P 〈 0. 05 ）. Conclusions Esmolol has a significant role in the prevention for induced intubation response for elderly hypertensive patients with coronary artery disease. It suits further extensive promotion use for clinical.
出处
《职业卫生与病伤》
2013年第1期52-54,共3页
Occupational Health and Damage
关键词
艾司洛尔
老年
高血压冠心病
诱导插管
esmolol
elderly
hypertensive with coronary artery disease
induced intubation
