期刊文献+

尿酸水平与冠心病及其病变程度相关性研究 被引量:3

Relativity research between serum uric acid level and coronary disease
暂未订购
导出
摘要 目的探讨血尿酸水平与冠心病及其病变程度的相关性,为防治冠心病提供客观的实验室指标。方法将选择性冠状动脉造影明确的冠心病患者80例作为冠心病组,非冠心病患者35例作为正常组,比较2组血尿酸水平;将冠心病组分为单支病变和多支病变2个亚组,观察比较冠脉狭窄程度与血尿酸水平的关系。结果冠心病组血尿酸水平明显高于非冠心病组(P<0.01);冠心病组中,多支病变组血尿酸水平明显高于单支病变组,且随着冠脉狭窄程度加重,血尿酸水平亦逐步提高。结论高尿酸血症是引起冠心病的危险因素之一,可能为病情严重程度的一个重要指标。 Objectives To observe the correlation between serum uric acid level and coronary disease and the grade of cervical lesions for providing objective laboratory index to prevent coronary disease. Methods 80 cases with coronary disease of explicit coronary arteriongraphy were selected as coronary group and 35 patients without coronary disease were selected as the control group.Serum uric acid level in 2 groups were compared. The coronary disease group were divided into 2 groups, single branch lesion group and multiversity disease group. Results The patients with elevated serum uric acid of coronary disease group were more than that of non coronary disease group (P〈0.01). In coronary heart disease group, multi-vessel group serum uric acid levels were significantly higher than that of single branch lesion group, and with the degree of coronary stenosis increased, serum uric acid level also ~adually improved. Conclusion Hyperuricemia was one of the dangerous factors to cause coronary disease, and may be an important index for severity of illness.
出处 《基层医学论坛》 2013年第4期428-430,共3页 The Medical Forum
关键词 冠心病 冠状动脉病变 血尿酸 相关性 Coronary diseas Coronary artery lesions Blood uric acid Correlation
  • 相关文献

参考文献8

  • 1Klein R, Klein BE, Comoli J, et al.Serum uric acid[J].Arch Intern Med, 1973,132(3) :401-410.
  • 2Fang J.Serum uric acid and cardiovascular mortality,the NHLANS epidemioflogic follow-up study, 1971-1992 [J].JA-MA,2000,283 (18) :2404-2410.
  • 3Levin W,Dyer AR,Shelelle RB.et al.Serum uric acid and ll.5yearmortality of Midle-aged women [J].J Clin Epidemiol, 1989,42 (3): 257-267.
  • 4Woo J,Swamination R,Cockram C,et al.Association between serum uric acid and some cardiovascular risk factors in a Chinese population [J]. Postgrad Med J, 1994,70( 5 ) : 486-491.
  • 5尹潍.高尿酸血症和痛风[J].国外医学(内分泌学分册),2003,23(4):219-221. 被引量:36
  • 6Lehto S, Niskanen L, Ronnemaa T,et al.Serum uric acid is a strongpredictor of stroke in patients with non-insulin-dependent diabetes melitus[J].Stroke, 1998,29 (3) : 635-639.
  • 7吕建国,梁爽霖.冠心病与血尿酸的关系[J].中国心血管杂志,1998,3(4):288-289. 被引量:53
  • 8刘湘源,肖玉兰,任素琴,唐丽君,张莉芸.老年人高尿酸血症调查及影响因素分析[J].中华风湿病学杂志,2005,9(5):280-283. 被引量:118

二级参考文献11

  • 1胡志勇.155例高尿酸血症临床分析[J].铁道医学,1994,22(3):151-152. 被引量:3
  • 2Ruilope LM, Garcia-Puig J. Hyperuricemia and renal function.Curr Hypertens Rep, 2001, 3: 197-202.
  • 3Simmonds HA, McBride MB, Hatfield PJ, et al. Polynesian women are also at risk for hyperuricaemia and gout because of a genetic defect in renal urate handling. Br J Rheumatol, 1994, 33:932-937.
  • 4Choi HK, Atkinson K, Karlson EW, et al. Weight gain, obesity,and incident gout in a large, long-term, prospective cohort study.Program and abstracts of the American College of Rheumatology 66th Annual Scientific Meeting. New Orleans: Louisiana, 2002.1593.
  • 5Nakanishi N, Tatara K, Nakamura K, et al. Risk factors for the incidence of hyperuricaemia: a 6-year longitudinal study of middle-aged Japanese men. Int J Epidemiol, 1999, 28: 888-893.
  • 6Johnson R J, Kang DH, Feig D, et al. Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease? Hypertension, 2003, 41: 1183-1190.
  • 7Dincer HE, Dincer AP, Levinson DJ. Asymptomatic hyperuricemia: to treat or not to treat. Cleve Clin J Med, 2002, 69:594、 597、600-602.
  • 8张振文.痛风的危险因素[J].国外医学(内分泌学分册),1997,17(3):141-143. 被引量:77
  • 9杜蕙,陈顺乐,王元,徐力青.上海市黄浦区社区高尿酸血症与痛风流行病学调查[J].中华风湿病学杂志,1998,2(2):75-78. 被引量:197
  • 10邱朝晖,曹奕,郑安琳,殷民德.高尿酸血症与高血压的关系[J].国外医学(心血管疾病分册),2001,28(1):9-11. 被引量:192

共引文献198

同被引文献23

引证文献3

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部