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妊娠期肝内胆汁淤积症早期诊治的临床意义 被引量:3

Clinical significance of early diagnose and treatment for intrahepatic cholestasis of pregnancy
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摘要 目的探讨早期筛查妊娠期肝内胆汁淤积症(Intrahepatic cholestasis of pregnancy,ICP)对围生儿愈后的改善作用。方法 2010年9月至2011年9月在我院分娩的179例ICP患者,以孕中晚期是否将血清胆汁酸作为常规检查项目为标准分为A、B两组,对两组ICP的分度、早产、羊水污染、新生儿窒息进行对比分析。结果 179例ICP患者中仅有A组42例孕中晚期作血清胆汁酸检查,A组在重度ICP、死胎、羊水污染、新生儿窒息、早产等方面明显低于B组,差异有统计学意义(P<0.05)。结论早期诊治ICP非常重要,可减少围生儿发病率及死亡率,达到提高产科质量、减少产科纠纷的目的。 Objective To explore whether or not the early screen of ntrahepatie eholestasis of pregnancy (ICP)improve the perinatal children prognosis and the relationship between physician and patient. Methods One hundred seventy-nine patients in our hospital from Sep-26 2010 to Sep-25 2011 were involved in the study. They were divided into A and B groups according to whether ser- um bile acid was used as the regular test in pregnant women at middle and late stages. The ICP degree, premature birth, amniotie fluid pollution and neonatal suffocation were eompared between the two groups. Results Only 42 pregnant women in the group A received the serum bile acid test. The severe ICP, stillbirth, amniotie pollution, neonatal asphyxia and preterm birth in the group A were signifi- cantly lower than that in the group B ( all P 〈 0. 05 ). Conclusions It is very important to diagnose ICP at early time in order to de- crease mortality and morbidity rate of perinatal children. This may improve the quality of obstetric and at the same time decrease the rate of medical disputes.
作者 陈徐
出处 《实用医院临床杂志》 2013年第2期76-77,共2页 Practical Journal of Clinical Medicine
关键词 妊娠 肝内胆汁淤积 诊治 纠纷 Pregnancy Intrahepatie eholestasis of pregnancy Diagnosis Disputes
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