摘要
目的 了解慢性肾炎患者尿表皮生长因子（ＥＧＦ）含量的变化及意义。方法 用放射免疫法测定尿ＥＧＦ含量。结果 １３７例肾功能正常组患者尿中ＥＧＦ含量显著高于正常组（Ｐ〈０．０１），３９例肾功能不全组患者尿中ＥＧＦ含量显著低于正常人组（Ｐ〈０．０１）。结论 肾功能正常组尿ＥＧＦ与肾功能不全组尿ＥＧＦ存在显著差异，说明ＥＧＦ在慢性肾炎的病变发生、发展中可能有重要的意义。
Objective:To research on the significance and change of urine EGF in patients with chronic glomerulonephritis(CGN).Methods:The level of urine EGF was measured using radioimmunoassay(RIA).Results:The EGF levels of 137 patients with normal renal functions were significantly higher than that of the normal controls(P<0 01),and 39 patients with renal insufficiency had EGF levels significantly lower than that of the normal controls(P<0 01).Conclusion:For the urine EGF levels were significantly different between normal renal function patients and renal insufficiency patients,the EGF should be closely related to the recurrence and development of CGN.
出处
《福建医药杂志》
CAS
2000年第5期8-9,共2页
Fujian Medical Journal
基金
福建省自然基金
关键词
慢性肾炎
尿表皮生长因子
EGF
诊断
Chronic glomerulonephritis\ Urine epidermal growth fact?
