摘要
目的探讨复方甘草酸苷联合异维A酸隔日疗法治疗重度痤疮的疗效。方法将112例患者随机分为治疗组(56例)和对照组(56例)。对照组:患者体重≥50kg者,隔日口服异维A酸10mg,3次/d;体重<50kg者,隔日口服异维A酸10mg,2次/d。治疗组:患者在对照组的基础上加用复方甘草酸苷3片,3次/d,两组均外用异维A酸红霉素凝胶,1次/d,疗程均为6周。结果 治疗组和对照组有效率分别为91.07%和75.00%,两组疗效差异有统计学意义(P=0.023)。结论复方甘草酸苷联合异维A酸隔日疗法治疗重度痤疮疗效良好。
Objective To investigate the clinical effect of compound glycyrrhizin combined with intermittent isotretion on severe ache. Methods One handred and twelve patients qualified with the inclusion criteria were randomly divided into treatment group （n = 56）and control group（ n = 56）. In the control group the isotretinoin was given every other day. The patients whose weight≥50 kg were given the drug 10 rag, 3 times a day, and the patients whose weight 〈50 kg were given the drug 10 mg, 2 times a day. In the treatment group the patients were added the compound glycyrrhizin 3 tablets, 3 times a day, on the basic treatment of control group. The patients of two groups were given isotretinoin erythromycin gel for external use, once a day . The course of treatment was 6 weeks. Results After 6 weeks＇ treatment, the effective rates of the treatment group and the control group were 91.07% and 75.00% respectively. There was significant difference between two groups （P = 0. 023）. Conclusion Thetherapeutic effect of compound glycyrrhizin combined with intermittent isotretinoin on severe ance is better.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2013年第3期326-327,共2页
The Chinese Journal of Dermatovenereology
