摘要
吡美莫司是一种新型的免疫抑制剂,1%吡美莫司乳膏具有较佳的皮肤渗透性及较低程度的经皮吸收,不会发生全身免疫抑制,没有长期外用激素的副作用。目前用于湿疹、皮炎、白癜风、脂溢性皮炎等多种皮肤病,显示有良好的效果,较小的不良反应。提示该药在皮肤科具备广阔的应用前景。
Pimecrolimus is a new kind of immunosuppressants. Pimecrolimus 1% cream appears to have more favorable skin permeation due to its lower degree of percutaneous absorption which is none of systemic immunosuppressive potential, lack of side effects of topical corticosteroids for a long time usage. Pimecrolimus has been used in the treatment of many dermotoses, such as eczema, dermatitis, vitiligo and soborrheic dermatitis which have shown favorable results with minimum adverse effects. The studies indicated that pimecrolimus would have much prospect for the treatment of cutaneous disorders in dermatology.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2013年第3期309-311,共3页
The Chinese Journal of Dermatovenereology
