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子宫内膜间质肉瘤5例临床病理分析 被引量:4

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摘要 目的探讨子宫内膜间质肉瘤(endometrial stromal sar-coma,ESS)的临床病理特点、诊断、鉴别诊断及免疫表型。方法回顾性分析5例ESS患者的临床资料,探讨其病理特点、免疫表型及预后等相关因素。结果 5例ESS中,低度恶性4例,高度恶性1例,镜下见低度恶性密集排列的类似增殖期子宫内膜间质细胞围绕螺旋小动脉样的血管分布,核分裂少见,高度恶性瘤细胞大,异型性明显,小血管数量减少,核分裂多见,浸润明显,伴坏死,免疫表型:CD10、vimen-tin、ER、PR均阳性,CK、CD34、Melan-A均阴性。结论 ESS是女性生殖道少见肿瘤,术前常误诊为平滑肌瘤,确诊主要依靠组织病理学、免疫表型来判断肿瘤有无浸润及恶性程度的高低。CD10可作为ESS的鉴别诊断的重要标记之一。
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2013年第2期206-208,共3页 Chinese Journal of Clinical and Experimental Pathology
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