摘要
目的探讨重型颅脑损伤（sTBI）患者术中持续脑灌注压（CPP）监测的意义。方法解放军第一O一医院2009年6月至2011年12月收治的63例sTBI患者根据预后情况分为较好（GOS4—5分）及较差（GOS1—3分）两组，对两组患者术中CPP、平均动脉压（MAP）及颅内压（ICP）的变化进行相关性分析。结果两组间ICP、CPP总体差异有统计学意义（P〈0．05），而两组问MAP总体差异无统计学意义（P〉0．05）；各组内ICP、MAP及CPP在不同时间点变化的差异有统计学意义（P〈0．05）；两组间ICP、MAP及CPP在不同时间点变化的差异有统计学意义（P〈0．05）。结论术中持续CPP监测有助于术者及时判断和处理术中出现的病情变化，对改善sTBI患者的预后可能有着积极的临床意义。
Objective To explore the significance of intraoperative continuous monitoring of cerebral perfusion pressure （CPP） in the treatment of patients with severe traumatic brain injury （sTBI）. Methods We made an observational retrospective study involving a group with 63 patients diagnosed as sTBI from June 2009 to December 2011. According to the prognosis, patients were divided into two group： the good group （ GOS 4 -5 ） and the poor group （ COS 1 - 3 ）. We made multiple correlations to analyze the variance of intraoperative CPP, MAP, and ICP between the two groups. Statistical signification was P 〈 0.05. Results There were significant differences between the two groups in the variance of ICP and CPP （ P 〈 0. 05 ）, and MAP fluctuations between the two groups did not have statistical significance （ P 〉0.05）. The changes of intraoperative ICP, MAP, and CPP at different time points showed significant differences and statistical signification （ P 〈 0. 05 ） , whether in groups or between groups. Condusion Intraoperative continuous monitoring of CPP can help surgeons to judge and deal with the intraoperative condition changes timely and may even have a positive clinical significance to improve the prognosis of sTBI patients.
出处
《中华神经外科杂志》
CSCD
北大核心
2013年第2期153-156,共4页
Chinese Journal of Neurosurgery
关键词
外伤性脑损伤
脑灌注压
颅内压
平均动脉压
预后
Traumatic brain injury
Cerebral perfusion pressure
Intracranial pressure
Mean artery pressure
Prognosis
