摘要
目的应用彩色多普勒超声定量评价左房各功能参数以探讨冠心病患者左房功能的变化。方法选择因胸痛、胸闷住院的患者125例,其中冠心病组90例,非冠心病组35例,冠心病组又分单、双、三支病变亚组,每亚组30例。应用彩色多普勒超声诊断仪检测所有受试者左房内径(LAD)、面积(LAA)、容积(LAV)、左房射血分数(LAEF)、左房壁节段运动速度(VA-LA)、房间隔运动速度(VA-IAS)等指标。结果冠心病组患者左房内径、面积、容积明显增加,LAEF、VA-LA、VA-IAS明显低于非冠心病组(P<0.01)。单支病变组较非冠心病组左房面积射血分数(LAA-EF)、左房容积射血分数(LAV-EF)、VA-LA和LVEF减低;双支及三支病变组患者左房内径、面积、容积均明显大于单支病变组及非冠心病组,而LAA-EF、LAV-EF、VA-LA、VA-IAS和LVEF则明显减低(P<0.001)。结论冠心病的存在可削弱左房的功能,并随冠状动脉病变程度变化而加重,左房游离壁心肌舒张末期速度是反映冠心病患者左房功能变化的敏感指标。
Objective To discuss the changes of left atrial function by evaluating the parameters using colour Dop- pler echocardiography in patients with coronary heart disease. Methods One hundred and twenty-five patients with chest pain and chest tightness were included in this study, in which there were 90 patients with coronary heart disease （CHI））, 35 patients with non-coronary heart disease （NCHD）. For patients with CHD, there were 30 patients with single-vessel disease, 30 with double-vessel disease and 30 with triple-vessel disease. Values of left atrial diameter （LAD）, area （LAA）, volume （LAV）, left atrial ejection fraction （LAEF）, the velocity of left atrial wall （VA-LA）, the velocity of interatrial septum （VA-IAS） were measured by colour Doppler echocardiography in all patients. Results There were significant increases in LAD, LAA and LAV in patients with CHD. The values of LAEF, VA-LA and VA-IAS were significantly lower in patients with CHD than those in patients with NCHD （P 〈 0.01）. The values of LAA-EF, LAV-EF, VA-LA and LVEF were significantly lower in sin- gle-vessel disease group than those in NCHD group. Values of LAD, LAA and LAV were significantly greater, but values of LAA-EF, LAV-EF, VA-LA, VA-IAS and LVEF were significantly lower, in double-vessel and triple-vessel disease group than those of single-vessel disease group and NCHD group （P 〈 0.001）. Conclusion Coronary heart disease can impair left atrial function, which was aggravated with the severity of coronary lesions. The value of VA-LA was the sensitive parameter for the change assessment of left atrial function in coronary heart disease.
出处
《天津医药》
CAS
北大核心
2013年第2期136-138,共3页
Tianjin Medical Journal
