摘要
珊瑚树(Viburnum odoratissimum)是一种通经活络的民间药用植物,它主要含有二萜、三萜、黄酮、倍半萜、木脂素、香豆素苷类化合物。二萜类化合物中vibsanin型是其特征化合物,分为3种亚型结构即十一元环型、七元环型和重排型,代表化合物为vibsanin B、vibsanin C和neovibsanin A。珊瑚树具有细胞毒、抑菌、鱼毒及抑制植物生长等活性,其中细胞毒活性为主要生物活性。
Viburnum odoratissimum is a folk medicinal plant, it can dredge the meridian passage and contains mainly diterpenes, triterpenes, flavonoids, sesquiterpenes, lignans, coumarin glycosides, etc. Vibsanintype diterpenoids are the characteristic compounds of V. odoratissimum, and are divided into eleven-membered ring, seven-membered ring, and rearrangement-type. Vibsanin B, vibsanin C and neovibsanin A are the representative compounds of the three subtypes of vibsanin-type diterpenoids respectively. V. odoratissimum has cytotoxic activity, antibacterial activity, fish piscicidal activity and activity of inhibiting the growth of plants, etc. Cytotoxic activity is the main biological activity.
出处
《药学学报》
CAS
CSCD
北大核心
2013年第3期325-332,共8页
Acta Pharmaceutica Sinica
基金
国家自然科学基金资助项目(81273544)
国家科技重大专项资助项目(2009ZX09103-406)
关键词
珊瑚树
化学成分
二萜
生物活性
细胞毒
Viburnum odoratissimum
chemical constituents
diterpenes
biological activities
cytotoxic
