摘要
人与其他哺乳动物一样，有明显的昼夜节律，光照是昼夜节律产生及调节最重要的授时因子。光线通过视杆细胞、视锥细胞及表达黑视素的视网膜神经节细胞（mcRGCs），经视网膜-下丘脑束（RHT）传导至视交叉上核（SCN）等视觉中枢，共同调节昼夜节律、瞳孔对光反应等非形觉功能。青光眼的病理基础是RGCs受损，进而累及mcRGCs，会影响患者的昼夜节律。就青光眼及实验性高眼压对昼夜节律影响的研究现状进行综述。
Like other mammals,human has obvious circadian rhythm, and light is recognized as the principal circadian synchronizer. Rod/cone photoreceptors of the outer retina and the melanopsin-containing retinal ganglion cells （mcRGCs）of the inner retina mediate non-image forming visual responses including entrainment of the circadian clock to the ambient light, the pupillary light reflex （PLR） , and light modulation of activity by means of a set of mcRGCs projecting to the suprachiasmatie nucleus （SCN） through retinohypothalamic tract （ RHT）. Glaucoma is a group of diseases which cause degenerative changes and loss patients with glaucoma will be interrupted. The progress in hypertension on circadian rhythm was reviewed. of RGCs including mcRGCs,so the circadian rhythm of the study on the effect of glaucoma and experimental
出处
《中华实验眼科杂志》
CAS
CSCD
北大核心
2013年第3期303-306,共4页
Chinese Journal Of Experimental Ophthalmology
关键词
青光眼
昼夜节律
黑视素
Glaucoma
Circadian rhythm
Melanopsin
