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狼疮脑病的临床相关因素分析(附76例报告) 被引量:7

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摘要 目的:探讨系统性红斑狼疮脑病(NPSLE)发生的临床相关因素。方法:对76例SLE患者的临床指征进行回顾性分析。结果:单因素分析示病程、肢端红斑坏死、面部光敏感皮疹、血沉快、血补体3(C3)降低、血白细胞减少、ALT升高、AST升高、血免疫球蛋白升高、A/G倒置、抗磷脂抗体、抗核糖体P蛋白抗体、是否用肾上腺皮质激素治疗均与SLE脑病的发生相关(P<0.05);多因素回归分析(logistic analysis)示血白细胞、肢端红斑坏死、A/G倒置、抗核糖体P蛋白抗体进入logistic多元回归方程(P<0.05)。结论:上述临床指征与SLE脑病的发生有关,其中血白细胞、肢端红斑坏死、A/G倒置、抗核糖体P蛋白抗体是SLE患者发生脑病最重要的临床相关因素。
作者 梅坚 张虹
出处 《中国社区医师(医学专业)》 2013年第4期47-48,共2页
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