摘要
目的观察复方阿嗪米特联合多潘立酮治疗功能性消化不良的疗效。方法选择2010年2月—2012年3月我院门诊120例符合罗马Ⅲ功能性消化不良诊断标准患者按随机数字法分为两组,每组各60例。对照组给予多潘立酮(10mg,3次/d,餐前30min口服);治疗组在对照组基础上联合复方阿嗪米特肠溶片(2片,3次/d,餐后服)治疗,治疗前及治疗4周后填写治疗效果表格及不良反应表格。结果实验组除上腹烧灼感外,上腹痛、餐后饱胀不适、早饱感改善较明显,临床症状积分及总有效率与对照组比较差异有统计学意义(P<0.05)。结论复方阿嗪米特联合多潘立酮较单用多潘立酮可明显提高治疗功能性消化不良疗效,不良反应少。
Objective Effect of compound azintamide combined with domperidone on functional dyspepsia treatment effect. Methods 120 outpatients with functional dyspepsia with Rome m diagnostic criteria in patients with were randomly di- vided into two groups, each of the 60 eases, the control group received domperidone （10mg, 3 times daily before meals, 30min oral）, The treatment group in the control group based on the joint compound azintamide enteric -coated tablets （2 tablets, 3 times a day, after meals. ） treatment, Before and 4 weeks after treatment in therapeutic effect and adverse reaction of form form. Results The experimental group in addition to epigastrie burning sensation, epigastrie pain, postprandial fullness discomfort, early satiety is much improved, Clinical symptom scores and the total efficiency in comparison with the control group had statisti- cal significance （ P 〈 0. 05 ）. Conclusion Compound azintamide combined with domperidone domperidone than single use can significantly improve the treatment of functional dyspepsia curative effect, less adverse reaction.
出处
《临床合理用药杂志》
2013年第6期37-38,共2页
Chinese Journal of Clinical Rational Drug Use
