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弥散加权成像对紫杉醇周方案治疗乳腺癌的疗效评估

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摘要 目的研究磁共振弥散加权成像评估紫杉醇周方案治疗乳腺癌后残留病灶的价值。方法前瞻性选取120例术前进行紫杉醇周方案治疗乳腺癌患者的131个病灶,采用化疗过程中乳腺癌的表观弥散系数差值的变化,评价紫杉醇周方案治疗乳腺癌的疗效。结果紫杉醇治疗乳腺癌新辅助化疗后,经EPI-DWI评估,120个乳腺癌病灶中,化疗有效62.5%(75/120),其中CR12个,PR63个;无效37.5%(45/120),其中18个PD,27个SD,化疗有效组和无效组之间比率存在差异(P〈0.05)。EPI-DWI图测量肿瘤大小与病理测量肿瘤大小的关系两者之间没有统计学差异(P〉0.05);无效组ADC值变化变化较小(差值均数0.10±0.03),2者之间存在统计学差异(P〈0.05)。结论磁共振弥散加权成像可评价紫杉醇周方案治疗乳腺癌疗效。
出处 《中国药业》 CAS 2012年第A01期37-38,共2页 China Pharmaceuticals
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