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非甾体类抗炎药引起的胃十二指肠粘膜损害及其预防 被引量:4

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摘要 非甾体类抗炎药(NSAIDs)包括阿斯匹林、消炎痛、保泰松、炎痛喜康、布洛芬等,具有消炎解热和镇痛作用,被广泛用于治疗风湿热、风湿及类风湿性关节炎、骨骼、肌肉病变引起的疼痛等,近年来阿斯匹林还被用以抗血栓治疗。急性大剂量及长期服用NSAIDs均可引起上腹不适、胀满、疼痛,亦可无任何症状而出现上消化道出血及穿孔。
作者 蓝宇 吴文静
出处 《北京医学》 CAS 北大核心 1991年第3期166-168,共3页 Beijing Medical Journal
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同被引文献16

  • 1郑宝轩.急性胃粘膜病变69例分析[J].华夏医学,1996,9(2):180-181. 被引量:1
  • 2Laine L.Proton pump inhibitor co-therapy with nonsteroidal antiinflammatory drugs-nice or necessary?.Bey Castroenterol Disord,2004,4(Suppl 4):S33-41.
  • 3Bardhan KD.Bjrnason I,Scott DL,et al.The prevention and healing of acute NSAID associated gastreduodenalmucosal damage by misoprostol.Br J Rheumatol,1993,32(11):990-995.
  • 4Taha AS,Dahill S,Sturrock RD,et al.Predicting NSAID related ulcers assessment of clinical and pathological risk factors and importance of differences in NSAID.Gut,1994,35(7):891-895.
  • 5Dijkmans BA,Janssen M,Vandenbroucke JP,et al.NSAID associated upper gastrointestinal damage in patients with rheumatoid arthritis.Scand J Gastroenterol Suppl,1995,30(212):105-108.
  • 6Cappell MS,Schein JR.Diagnosis and treatment of nonsteroidal antiinflammatory drug-associated upper gastrointestinal toxicity.Gastroemerol Clin North Am,2000,29(1):97-124.
  • 7Voutilainen M,Sokka T,Juhola M.Nonsteroidalant-inflammatory drug-associated upper gastroin-testinal lesions in rheumatoid arthritis patients.Relationships to gastrichistology Helicobactor Pylori infection,and other risk factors for peptieulcer.ScandJ Gastroenterol,1998,33(8):811-816.
  • 8Aalykke C,Lauritsen Ji,Hallas J.Helicobacter pylor and risk of ulcer bleeding among users of nonsteroidalanti-inflammatory drugs:a case-control study.Gastroenterology,1999,116(6):13059-1309.
  • 9Lanas A,Scheiman J.Low-dose aspirin and upper gastrointestinal damage:epidemiology,prevention and treatment.Curr Med Res Opin,2007,23(1):163-173.
  • 10赖礼铎 李莹.上消化道出血的诱因分析[J].广州医药,1990,6(3):14-14.

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