摘要
对于手术切除的胰头癌患者，胰十二指肠切除（PD）标本切缘情况是影响预后的关键因素。文献报道R1切缘发生率差异极大，并且R1切缘发生率与临床结果不一致。这种情况的发生与没有对PD标本切缘的组成及切缘R1的定义等形成统一的认识、没有统一的取材方法有关，还与对胰头部肿瘤的具体起源诊断不准确有关。文中将就PD标本切缘的组成、R1的定义标准、R1与取材方法的关系、切缘与预后的关系、切缘和肿瘤起源的关系等方面作一综述。
Resection margin involvement of pancreaticoduodenectomy is an key prognostic factor for pancreatic head cancer.However,there is a wide variation of reported microscopic margin involvement (R1) rate in the literature,and there is discrepancy between the R1 rate and clinical outcome.Recent studies indicate that the variation and the discrepancy are caused by confusing nomenclature,controversy regarding the difinition of R1,lack of standardization of pathological examination,and inaccurate diagnosis for the pancreatic head mass.This review summarizes the composition and nomenclature of the circumferential resection margin,the difinition of R1,the method of pathological examination,the relationship between R1 rate and prognosis,and the relationship between resection margin involvement and tumor origin.
出处
《中华肝胆外科杂志》
CAS
CSCD
北大核心
2013年第2期156-160,共5页
Chinese Journal of Hepatobiliary Surgery
