摘要
目的对江西地区社区糖尿病足感染菌及耐药性进行综合评价,为本地区社区糖尿病足感染菌的经验治疗提供依据。方法回顾性分析84例糖尿病足感染患者溃疡处感染菌及耐药性。结果 84例糖尿病足感染患者中68例患者溃疡处分离出82株病原菌,其中有14例分离出2种病原菌。混合感染率为(20.6%),其中革兰阳性球菌58株,占70.7%,其中金黄色葡萄球菌38株、表皮葡萄球菌11株、粪肠球菌9株;革兰阴性菌22株,占26.8%,其中肠杆菌科细菌共18株(分别为大肠埃希菌12株、变形杆菌1株、阴沟肠杆菌1株、产气肠杆菌1株、肺炎克雷伯杆菌1株),非发酵菌4株;真菌2株,占2.4%。各种病原菌对常用抗菌药物的耐药率也各不相同。结论糖尿病足感染部分为混合性感染,其致病菌多为多重耐药,为有效治疗糖尿病足感染菌,应结合糖尿病足感染的临床特征,根据药敏结果选择有效抗菌药物,防止滥用抗生素和耐药菌株的出现,提高治愈率。
Objective To comprehensively evaluate the drug resistance of diabetic foot infections bacteria of communities in Jiangxi area,and to provide the basis for empirical treatment of diabetic foot infection bacteria in communities in the region.Methods 84 cases of diabetic foot infections in patients with ulcer infected with bacteria and their drug resistance were retrospectively analyzed.Results 82 strains of bacteria were isolated from 68 cases of ulcer places out of 84 cases of diabetic foot infected patients,including 14 cases with isolated pathogens.The mixed infection rate was 20.6%（14/68）,in which there were 58 strains of Gram-positive cocci,accounted for 70.7% of the total.And there were 38 strains of Staphylococcus aureus,11 strains of Staphylococcus epidermidis,9 strains of Enterococcus faecalis;22 strains of Gram-negative bacteria strains,totally accounted for 26.8%.There were 18 strains of Enterobacteriaceae,including 12 strains of Escherichia coli,Proteus,1 strain of Enterobacter cloacae,1 strain of Enterobacter aerogenes,1 strain of Klebsiella pneumoniae,4 strains of non-fermenting bacteria（4 strains of Pseudomonas aeruginosa）;and there were two fungi,accounted for 2.4%.The antimicrobial resistance rates of pathogens varied.Conclusion Part of the diabetic foot infection is mixed infections.Its pathogens are multi-drug resistant.In order to achieve effective treatment of diabetic foot infection bacteria,we should consider the clinical features of diabetic foot infections,and prevent misuse of antibiotics and the emergence of resistant strains according to the test results of susceptibility of antimicrobial agents,and therefore improve the cure rate.
出处
《检验医学与临床》
CAS
2013年第4期423-424,共2页
Laboratory Medicine and Clinic
关键词
糖尿病足
病原菌
抗菌药物
diabetic foot
pathogens
antibacterial drug
