摘要
目的探讨内镜智能分光比色技术(fuji intelligent chromo endoscopy,FICE)结合放大内镜对慢性萎缩性胃炎(chronic atrophic gastritis,CAG)的诊断价值。方法回顾分析经胃镜及病理组织学检查明确诊断为慢性胃炎的398例患者的资料,行FICE放大内镜检查者178例(FICE组),普通内镜检查者220例(普通内镜组)。内镜下对患者胃黏膜进行仔细观察,同时取组织行病理组织学检查;FICE组对胃黏膜小凹形态进行分型。结果 FICE组内镜下CAG胃黏膜具有特征性改变,表现为胃小凹的增宽且分布稀疏,胃黏膜病灶区的胃小凹形态主要表现为C、D及E型。FICE组对CAG诊断的符合率、敏感度、特异性和阳性预测值、阴性预测值分别为90.4%、86.2%、93.0%、87.5%、92.1%,均明显优于普通内镜组的69.1%、37.3%、85.5%、57.1%、72.5%(P<0.05)。结论 FICE技术结合放大内镜诊断CAG敏感性、特异性和准确性都较理想,并可精确地引导活检,避免不必要的活检创伤,减轻患者的痛苦及经济负担。
Objective To evaluate the value of fuji intelligent chromoendoscopy（FICE） combined with magnification endoscopy in the diagnosis of chronic atrophic gastritis（CAG）.Methods Data of 398 patients with chronic gastritis diagnosed by endoscopy and histopathological examination were retrospectively analyzed.Among these patients,FICE magnification endoscopy was performed in 178（FICE group） and ordinary endoscopy in 220（ordinary group）.Gastric mucosa was observed by endoscopy and was compared with histopathological examination.Gastric foveolar phenotype was determined by FICE.Results CAG patients in FICE group had characteristic changes in gastric mucosa,showing an increase in width of gastric pits and a decrease in distribution.Gastric pits mainly showed type C,D and E in gastric mucosal lesions.The coincidence rate,sensitivity,specificity,positive predictive value and negative predictive value were,respectively,90.4%,86.2%,93.0%,87.5% and 92.1% in FICE group,and 69.1%,37.3%,85.5%,57.1% and 72.5% in ordinary group.There were significant differences between the two groups（P0.05）.Conclusion FICE combined with magnification endoscopy shows higher sensitivity,specificity and accuracy in the diagnosis of CAG,and can precisely guide biopsy,avoid unnecessary trauma and relieve patient＇s suffering and economic burden.
出处
《南昌大学学报（医学版）》
CAS
2012年第11期56-58,62,共4页
Journal of Nanchang University：Medical Sciences
关键词
萎缩性胃炎
慢性
内镜智能分光比色技术
放大内镜
atrophic gastritis
chronic
fuji intelligent chromoendoscopy
magnification endoscopy
