摘要
目的观察络衡方对高血脂症实验大鼠血液流变学的影响。方法喂饲高脂饲料及灌喂高脂溶液建立高血脂大鼠模型,检测生化指标。结果络衡方可显著降低高脂模型,大鼠的谷丙转氨酶、碱性磷酸酶、低密度脂蛋白、总胆固醇水平;血液流变学检测发现络衡方能显著降低全血黏度和红细胞压积。结论改善体内的脂肪代谢可能是络衡方治疗急性冠状动脉综合征的机理之一。
Objective To observe the effect of Luoheng prescription on hemorheology of rats. Methods By feeding rats with highfat diet and solution, a rat model of hyperlipidemia was established. Results Observation of bi ochemical parameters showed that Luoheng prescription could significantly reduce alanine aminotransferase, alkaline phosphatase, lowdensity lipoprotein, total cholesterol of fat rats. Hemorheological values showed Luoheng prescrip tion significantly reduced the whole blood viscosity and hematocrit. Conclusion Improving the body＇s fat metabolism may be one of the mechanisms of Luoheng prescription for acute coronary syndrome.
出处
《解放军药学学报》
CAS
2012年第6期495-498,共4页
Pharmaceutical Journal of Chinese People's Liberation Army
基金
国家青年科学基金项目
No.30901955
