摘要
目的:对产于湖北蕲春的艾叶进行化学成分分离与结构鉴定。方法:利用大孔树脂、SephadexLH-20、MCI gel CHP-20、制备型HPLC等色谱方法进行分离纯化,运用MS、UV、1 H-NMR、13 C-NMR及二维核磁共振等方法进行结构鉴定。结果:从蕲艾叶中分离到6个黄酮单体化合物,分别为5,7,3′,4′-四羟基二氢黄酮(1)、5,7,3′,4′-四羟基,6-甲氧基黄酮(2)、5,7,4′,5′-四羟基,3′,6-二甲氧基黄酮(3)、芹菜素(4)、木樨草素(5)和槲皮素(6)。结论:化合物1～3均为首次从该植物中分离得到。
Objective：The paper aims to isolate the chemical constituents of Artemisia argyi Levl. et Vant from QiChun county in Huibei province and identify their structures. Methods：The compound were isolated by macro absorption resin, Sephadex LH-20, MCI gel CHP-20, preparative HPLC and identified on the basis of physicochemical properties and spectral analysis, such as MS, UV, 1 H-NMR,13 C-NMR and 2D-NMR . Results： The results showed that six flavonoids compounds were identified as 5,7,3′,4′- tetrahydroxy, dirnethoxylflavonids （ 1 ）, 5,7, 3 ′, 4′-tetrahydroxy, 6-methoxylflavonids （ 2 ）, 5,7,4′, 5′-tetrahydroxy, 3 ′, 6-dimethoxy Conclusion： Howere, the compounds （ 1 ）- （ 3 ） were firstly isolated and i-dentified from this plant.
出处
《亚太传统医药》
2013年第2期4-6,共3页
Asia-Pacific Traditional Medicine
基金
国家重点基础研究发展计划基金资助项目(2009CB522900)
关键词
蕲艾
化学成分
黄酮化合物
QIAI（Artemisia argyi Levl et Vant. ev. qiai）
Chemical Consitituents
Flavonoids
