摘要
Acute basophilic leukemia (ABL) is a rare subtype of .acute myeloid leukemia (AML), accounting for 4%-5% of AML and less than 2% of all hematopoietic malignancies. It is usually characterized by a very rapid clinical course, symptoms of hyperhistaminemia, peptic ulceration, gastrointestinal cerebrovascular bleeding and resistance to therapy.^1 However, the clinical outcome of ABL remains disapp2ointing. Most patients died within 1 year after diagnosis.
Acute basophilic leukemia (ABL) is a rare subtype of .acute myeloid leukemia (AML), accounting for 4%-5% of AML and less than 2% of all hematopoietic malignancies. It is usually characterized by a very rapid clinical course, symptoms of hyperhistaminemia, peptic ulceration, gastrointestinal cerebrovascular bleeding and resistance to therapy.^1 However, the clinical outcome of ABL remains disapp2ointing. Most patients died within 1 year after diagnosis.