摘要
目的探讨超声软指标在产前诊断胎儿染色体异常中的价值。方法选取2010年1月到2011年4月间,到我院接受产前诊断超声检查的孕妇为研究对象,观察或测量以下超声软指标:鼻骨回声异常(NB)、心室内强回声点(EIF)、肠管强回声、脉络膜囊肿、轻度肾盂扩张,同时随访最终的染色体检查结果。结果在10603例孕妇中,有一项或多项超声软指标阳性的共有1741例,其中21-三体8例,18-三体8例。结论中孕期产前诊断超声筛查出2个或以上超声软指标异常,可更早提示胎儿染色体异常的可能性,降低染色体异常胎儿的漏诊率,并降低侵入性检查的比率。
Objective： To assess the value of ultrasonographic soft markers to prenatal diagnosis of fetal chromosomal abnormality Methods： Select the pregnant women who accepted prenatal diagnosis by ultrasound examination in our hospital during January 2010 to April 2011 as the research object,observed or measured following ultrasonographic soft markers such as nasal bone（NB）echo abnormality,echogenic intracardiac focus（EIF）,echogenic bowel,choroid plexus cyst,mild pyelectasis,and follow-up final chromosome results of all the cases.Results： In 10603 cases of pregnant women,we detect one or more ultrasound soft markers in 1741 patients,including 8 cases of trisomy 21and 8 cases of trisomy 18.Conclusion： The prenatal diagnosis of ultrasound during the second trimester in which we detect two or more abnormal ultrasonographic soft markers can earlier suggest the possibility of fetal chromosome abnormalities,and reduce the misdiagnosis rate,and also reduce the rate of invasive examination.
出处
《中国优生与遗传杂志》
2013年第2期39-40,47,共3页
Chinese Journal of Birth Health & Heredity
关键词
超声软指标
染色体异常
产前诊断
Ultrasonographic soft markers
Prenatal diagnosis
Chromosomal abnormality
