摘要
目的:测定体检人群中几种常见环境污染物质的含量,了解这些环境污染物质在正常人群中的内暴露程度。方法:采用GC、GC-MS、HPLC、ELISA等方法,对80例体检人群尿样中环境污染物的含量进行检测。结果:甲醛和甲苯的检出率分别为97.6%和41.2%;黄曲霉毒素M1(aflatoxin M1,AFM1)的检出率为91.4%;邻苯二甲酸二丁酯(dibutyl phthalate,DBP)的检出率为75.3%;有机磷的检出率在1.2%～41.2%之间;三种多氯联苯(polychlorinated biphenyl,PCBs)、氯丙嗪(chlorpromazine,CPZ)和4,5-二氯儿茶酚(4,5-dichlorocatechol,4,5-DCC)的检出率较低,检出人数均少于5例;三甲基氯化锡(trimethyltin-chloride,TMT)未检出。结论:部分环境污染物在体检人群中的内暴露程度较高,其对人体的影响和限值研究亟待加强。
Objective： To detect common environmental pollutants in human body. Methods： Urine samples were collected from 80 healthy subjects. Chromatography mass spectrometry （GC-MS） , HPLC and ELISA were applied to detect several common environmental pollutants in urine samples. Results： DBP and methylbenzene were present in 75.3% and 41.2% of urine samples. The methanal and AFM1 were found in most of urine samples （approximately 91 -97% ）. By contrast, PCBs, CPZ,4,5-DCC were found in less than 5 samples, but there was no TMT detected. Conclusion： Some of the environmental pollutants including carcinogens are detected in urine samples in this study.
出处
《浙江大学学报（医学版）》
CAS
CSCD
北大核心
2013年第1期14-18,共5页
Journal of Zhejiang University(Medical Sciences)
基金
浙江省重大科技专项基金(2010C13006)
浙江省卫生科研基金(2011KYA044)
关键词
环境污染物
职业暴露
尿
分析
甲醛
甲苯
黄曲霉毒素M1
酶联免疫吸附测定
色谱法
高压液相
气相色谱-质谱法
色谱法
气相
Environmental pollutants
Occupational exposure
Urine/analysis
Formaldehyde
Toluene
Aflatoxin M1
Enzyme-linked immunosorbent assay
Chromatography, highpressure liquid
Gas chromatography-mass spectrometry
Chromatography,gas
