摘要
目的探讨复方甘草酸苷联合硫普罗宁钠治疗酒精性肝硬化的疗效。方法将82例酒精性肝硬化患者随机分为观察组(n=41)与对照组(n=41),前者接受复方甘草酸苷联合硫普罗宁钠治疗,后者仅接受硫普罗宁钠治疗,现对比分析两组患者的疗效。结果 (1)治疗前,两组患者血清丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、总胆汁酸(TBA)、γ-谷氨酰转肽酶(GGT)相比差异无统计学意义(P>0.05);治疗后,观察组ALT、AST、TBA、GGT显著低于对照组(P<0.05)。(2)观察组治疗效果显著优于对照组(P<0.05)。结论复方甘草酸苷联合硫普罗宁钠可显著改善酒精性肝硬化的肝功能。
Objective To investigate the therapeutic efficacy of compound glycyrrhizin combined with sodium tiopronin in the treatment of alcoholic cirrhosis. Methods Eighty-two cases of alcoholic cirrhosis were randomly divided into the observation group （n = 41） and the control group （n = 41）, and the former received compound glycyrrhizin combined with sodium tiopronin, while the latter was given sodium tiopronin, and the therapeutic efficacies between the 2 groups were compared in this paper. Results （1）Before treatment, there were no significant differences in the serum alanine aminotransferase enzyme （ALT）, aspartate aminotransferase enzyme （AST）, total bile acid （TBA） and y-glutamyl transpeptidase （GGT） between the observation group and the control group （P 〉 0.05）. After treatment, the serum ALT, AST, TBA and GGT in the observation group were significantly lower than those in the control group, respectively （P 〈 0.05）. （2）The therapeutic efficacy of observation group was significantly better than that of the control group （P 〈 0.05）. Conclusion The compound glycyrrhizin combined with sodium tiopronin can improve the liver function in patient with alcoholic cirrhosis.
出处
《中国当代医药》
2013年第6期106-107,共2页
China Modern Medicine
关键词
复方甘草酸苷
硫普罗宁钠
酒精性肝硬化
疗效评价
Compound glycyrrhizin
Sodium tiopronin
Alcoholic cirrhosis
Therapeutic efficacy evaluation
