摘要
目的 探讨地塞米松联合10%葡萄糖酸钙辅助缩宫素预防产后出血的临床效果。方法 将128例产妇随机分为两组,对照组（n=64）：胎儿娩出后肌内注射缩宫素20 u;观察组（n=64）：进入第二产程后用5%葡萄糖注射液100 ml＋10%葡萄糖酸钙10 ml快速静脉滴注,胎儿娩出后肌内注射缩宫素20 u＋地塞米松10 mg。比较两组预防产后出血的临床效果。结果 观察组产后2 h出血量［（153.2±43.1）ml］以及产后24 h出血量［（419.3±77.8）ml］均少于对照组［（265.2±86.2）ml、（ 550.6±99.1）ml］（t=2.553、3.869,均P〈0.01）;观察组第二产程与第三产程时间［（26.6±11.1）min,（6.8±1.8）min］均明显地短于对照组［（55.4±12.4）min、（ 19.8±3.2）min］（t=3.452、3.213,均P〈0.01）。结论 应用地塞米松联合10%葡萄糖酸钙辅助缩宫素对产妇产后出血进行预防,其效果尤佳,可在临床上加以推广并应用。
Objective To investigate the clinical effect of the dexamethasone combined with 10% calcium gluconate auxiliary hormone oxytocin to prevent postpartum benorrhage.Methods 128 patients were randomly divide into two groups,control group（n=64）：intramuscular injection 20 u oxytocin after delivery of the fetus;observation group（n=64）：after entering the secind stage of labor,do a quick infusion with a 5% glucose 100ml＋10% of the calcum gluconate 10ml,intramuscylar injection 20u oxytocin＋dexamethasone 10 mg after deliver of the fetus.The clinical effects were compared in two groups of prevention of postpartum hemorrhage.Results Both the postpartum 2h bleeding of observation group[（153.2±43.1）]and the postpartum 24h bleeding[（419.3±77.8）] were lower than that of the control group[（265.2±86.2）ml,（550.6±99.1）ml]（t=2.553,3.869,all P〈0.01）;The time of second stage and third stage of labor for the observation group[（26.6±11.1）min,（6.8±1.8）min] were lower than that of the control group[（55.4±12.4）min,（19.8±3.2）min]（t=3.452,3.213,all P〈0.01）. Conclusion The effect of dexamethasone combined with 10% calcium gluconate auxiliary hormone oxytocin to prevent postpartum hemorrhage is aplus,which can be pronted and applied in clinical.
出处
《中国基层医药》
CAS
2013年第1期9-10,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
地塞米松
葡萄糖酸钙
缩宫素
产后出血
Dexamethasone
Calcium gluconate
Oxytocin
Postpartum hemorrhage
