摘要
目的探讨维生素E在新生儿缺氧缺血性脑病中的治疗作用。方法将62例新生儿缺氧缺血性脑病患儿随机分为两组，每组各31例，对照组按照新生儿缺氧缺血性脑病标准方案治疗，而干预组在标准方案基础上加用维生素E治疗。结果干预组患者3周后复查脑电图，与对照组比较差异无统计学意义（X2=0．28，P〉0．05）；两组治疗后肌酸激酶同工酶浓度比较差异有统计学意义（t=8．07，P〈0．05）。结论维生素E能减轻缺氧缺血性脑病患儿的大脑损伤，但是对患儿远期预后作用还需要进一步研究。
Objective To investigate the effect of vitamin E injection in the treatment of neo- natal hypoxic-ischemic encephalopathy. Methods Sixty-two cases of neonatal hypoxic-ischemic enceph- alopathy were randomly divided into two groups, intervention group（31 cases） and control group（31 ca- ses）. All cases received the standard treatment, and then the intervention group received the additional therapy of vitamin E for 15 days. Results Review the EEG after 15 days, there had no significant difference between the two groups（X2 =0. 28, P 〉 0. 05） ; CK-BB concentration in the two groups after treatment were significantly different （ t = 8.07, P 〈 0. 05 ）. Conclusions Vitamin E injection can re- duce the brain damage of neonatal hypoxic-ischemic encephalopathy, but further research is need improve the role on long-term prognosis.
出处
《中国实用医刊》
2013年第4期34-35,共2页
Chinese Journal of Practical Medicine
关键词
新生儿
缺氧缺血性脑病
维生素E
Neonatal
Hypoxic-ischemic encephalopathy
Vitamin E
