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多指标综合评分法正交试验优选枳芍散提取工艺 被引量:10

Study on extraction technology of Zhishi Shaoyao powder by multi-index comprehensive scoring method
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摘要 目的:优选枳芍散复方提取工艺。方法:采用正交试验,以芍药苷、柚皮苷、橙皮苷、新橙皮苷含量为指标性成分,考察浸泡时间、溶媒用量和提取次数对提取效果的影响,对实验结果进行综合分析。结果:优选出的提取工艺为16倍水浸泡30 min提取2次,每次1 h。结论:本试验方法对枳芍散的生产工艺具有一定的指导和参考意义。 Objective : To optimize the extraction technology of Zhishi Shaoyao powder. Methods: The orthogona! test was employed taking the contents of paeoniflorin, naringin, hesperidin and neohesperidin as the indexes and the influences on extraction results of soaking time, solvent dosage and extraction times were investigated, and were ana- lyzed by multi - index comprehensive scoring method. Results: The optimal extracting process was selected as fol- lows : 16 times of water consumption, soak for 30rain, extraction twice for 1 hour at each time. Conclusion: The ex- perimental method can serve as a guideline and reference for the production process of Zhishi Shaoyao powder.
出处 《药物分析杂志》 CAS CSCD 北大核心 2013年第2期193-196,共4页 Chinese Journal of Pharmaceutical Analysis
关键词 枳芍散 枳实 白芍 芍药苷 柚皮苷 橙皮苷 新橙皮苷 正交试验 提取工艺 多指标综合评分 Zhishi Shaoyao powder Aurantii Immaturus Fructus Paeoniae Radix Alba paeoniflorin naringin hesperidin neohesperidin orthogonal experiment extraction technology multi - index comprehensive scoring
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